Bayern Munich travel to Stuttgart this weekend and are ready to rotate their side with the Champions League semi-final second leg at Real Madrid to come four days later, manager Thomas Tuchel said.

The league title has been secured by Bayer Leverkusen, and with the Bundesliga's top five clubs guaranteed Champions League football next season, Saturday's clash between Bayern in second and third-placed Stuttgart is not crucial.

"We will give a few players the chance to pick up some rhythm," Tuchel said at his pre-match press conference on Friday.

"Of course, we will also take a few players out and allow ourselves to adapt the rhythm to Wednesday. 

"But that doesn't relieve us of our responsibility, that those who play have to fight and show grit there."

Bayern drew 2-2 at home to Madrid on Tuesday, a game Matthijs de Ligt missed due to injury, and the Dutch defender will also sit out the trip to Stuttgart in the hope of making the return game in Spain.

"Matthijs de Ligt won't be in the squad, as the plan is that he returns to training on Sunday, then we have got three days," Tuchel said.

"Jamal Musiala won't be in the squad. Same procedure there. Dayot Upamecano will try and train [Friday], so we'll see."

Leroy Sane scored in the draw with Madrid, after missing the last four league games through injury. The winger has played three Champions League games in that time and will be in the squad for Stuttgart.

"You always try to have a connection to the players. Leroy's been training with pain for seven or eight weeks, but is always available," Tuchel said.

"He has a high threshold. He deserves the utmost respect there. He's a bit short there at the moment because he can't train properly. 

"But he is in training and is coming to Stuttgart."

Bayern have 69 points, five ahead of Stuttgart with three games remaining.