Tottenham have sacked Nuno Espirito Santo just four months after appointing him as head coach.

Nuno signed a two-year deal to take over as Spurs boss at the end of June following four successful years in charge of Wolves.

Tottenham fans turned on the Portuguese during a 3-0 Premier League defeat at home to Manchester United on Saturday, his decision to substitute Lucas Moura for Steven Bergwijn greeted with chants of "you don't know what you're doing".

Media speculation on Sunday suggested Nuno's future was in immediate trouble, with chairman Daniel Levy reported to have opened talks with the board regarding a possible change.

The London club subsequently decided to end Nuno's short reign on Monday.

A statement read: "The club can today announce that Nuno Espirito Santo and his coaching staff Ian Cathro, Rui Barbosa and Antonio Dias have been relieved of their duties."

Spurs managing director of football, Fabio Paratici, added: "I know how much Nuno and his coaching staff wanted to succeed and I regret that we have had to take this decision.

"Nuno is a true gentleman and will always be welcome here. We should like to thank him and his coaching staff and wish them well for the future."

Nuno departs with Tottenham eighth in the top flight, having won five and lost five of their opening matches of the season.

The 47-year-old's 10 Premier League games at the helm is the lowest tally of any permanent Tottenham manager, one fewer than Jacques Santini's 11 in 2004.

Tottenham's 15 points gained under Nuno is one more than they achieved from Mauricio Pochettino's first 10 top-flight games in charge and one fewer than managed with Jose Mourinho as boss.

Spurs fired Nuno's compatriot Mourinho in April only 17 months after appointing him.