Eastern
| # | Team | PL | W | D | L | +/- | GD | PTS | Form | Next |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Memphis 901 | 16 | 11 | 2 | 3 | 32-14 | 18 | 35 | ||
| 2 | Louisville City FC | 16 | 10 | 3 | 3 | 32-13 | 19 | 33 | ||
| 3 | Tampa Bay Rowdies | 17 | 8 | 6 | 3 | 32-18 | 14 | 30 | ||
| 4 | Detroit City FC | 16 | 7 | 5 | 4 | 23-17 | 6 | 26 | ||
| 5 | Birmingham Legion | 15 | 7 | 4 | 4 | 14-12 | 2 | 25 | ||
| 6 | Pittsburgh Riverhounds | 16 | 7 | 3 | 6 | 24-23 | 1 | 24 | ||
| 7 | Indy Eleven | 15 | 6 | 3 | 6 | 22-25 | -3 | 21 | ||
| 8 | Miami FC | 17 | 5 | 6 | 6 | 19-18 | 1 | 21 | ||
| 9 | FC Tulsa | 17 | 5 | 3 | 9 | 21-32 | -11 | 18 | ||
| 10 | Loudoun United | 16 | 4 | 2 | 10 | 16-30 | -14 | 14 | ||
| 11 | Hartford Athletic | 15 | 3 | 3 | 9 | 15-23 | -8 | 12 | ||
| 12 | Atlanta United II | 16 | 3 | 1 | 12 | 16-39 | -23 | 10 | ||
| 13 | Charleston Battery | 15 | 2 | 3 | 10 | 15-30 | -15 | 9 | ||
| 14 | New York Red Bulls II | 16 | 1 | 3 | 12 | 9-30 | -21 | 6 |
Western
| # | Team | PL | W | D | L | +/- | GD | PTS | Form | Next |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | San Antonio FC | 15 | 11 | 1 | 3 | 24-13 | 11 | 34 | ||
| 2 | Colorado Springs Switchbacks FC | 14 | 11 | 0 | 3 | 31-17 | 14 | 33 | ||
| 3 | El Paso Locomotive | 18 | 8 | 4 | 6 | 36-22 | 14 | 28 | ||
| 4 | San Diego Loyal | 16 | 8 | 4 | 4 | 36-25 | 11 | 28 | ||
| 5 | Sacramento Republic FC | 15 | 8 | 4 | 3 | 19-12 | 7 | 28 | ||
| 6 | New Mexico United | 14 | 7 | 4 | 3 | 23-12 | 11 | 25 | ||
| 7 | Las Vegas Lights FC | 17 | 7 | 4 | 6 | 23-23 | 0 | 25 | ||
| 8 | LA Galaxy II | 18 | 7 | 3 | 8 | 26-33 | -7 | 24 | ||
| 9 | Oakland Roots | 19 | 5 | 9 | 5 | 29-27 | 2 | 24 | ||
| 10 | Rio Grande Valley FC | 16 | 7 | 1 | 8 | 23-24 | -1 | 22 | ||
| 11 | Phoenix Rising FC | 16 | 7 | 0 | 9 | 26-34 | -8 | 21 | ||
| 12 | Orange County SC | 16 | 4 | 5 | 7 | 24-27 | -3 | 17 | ||
| 13 | Monterey Bay FC | 15 | 4 | 0 | 11 | 20-37 | -17 | 12 |
