Andrea Pirlo warned his Juventus side they risk going the way of Real Madrid and Bayern Munich if they take SPAL lightly in Wednesday's Coppa Italia quarter-final tie.

SPAL knocked out Sassuolo in the last round and make the trip to the Allianz Stadium sitting fifth in Serie B as they seek a swift return to the top tier of Italian football.

Record 13-time Coppa winners Juve enter the game as strong favourites to progress to the semi-finals, where the winner of Tuesday's game between Inter and Milan would await.

However, in a month that has seen Madrid exit the Copa del Rey with defeat to third-tier Alcoyano and Bayern lose to second-tier Holstein Kiel in the DFB-Pokal, Pirlo is taking nothing for granted.

"There are a lot of possible risks because we are facing a Serie B team on paper. But if you look at the foreign cups, Bayern lost to a team from a lower division, as did Madrid," Pirlo told Juventus TV.

"We have to assume that it will be a difficult game. We need maximum concentration because we want to go through. They are a good team that are doing well in the league and cup.

"We of course have to be careful because the main objective is to pass through to the next round.

"They are a very good team that like to play football, play with three defenders and sometimes three forwards or half-strikers. It is a difficult team to face so we will have to be at our best to avoid losing."

Juve's Scudetto hopes took a major dent with defeat to Inter on January 17, but they have since responded with 2-0 wins over Napoli in the Supercoppa Italiana and Bologna in the league.

Pirlo now has near enough a fully-fit squad to choose from and believes that will be reflected on the results front.

"It means we can improve because we have great players back," he said. "I hope to finally have the whole squad available and we can then work on all the concepts, which we have not been able to do this season."

Rodrigo Bentancur will miss the cup tie but Matthijs de Ligt and Merih Demiral will return to the starting line-up after recovering from coronavirus and injury respectively.

"Bentancur will rest for sure because on Sunday he played the whole game with a hole in his foot," Pirlo said. "We had to put three stitches in - he made a big sacrifice and now he will need a few days of rest to absorb the bruise.

"Some players who played on Sunday will rest. De Ligt and Demiral will return and start from the beginning. Then for the rest we will have a competitive team.

Pirlo also confirmed Gianluigi Buffon will start against SPAL, with regular goalkeeper Wojciech Szczesny being given a breather.

Szczesny has conceded 16 goals in 14 league matches this term for a save percentage of 68.63, which is below the 74.42 he managed last season and 75.61 in 2018-19.

He made three saves against both Napoli and Bologna to keep successive clean sheets, but Pirlo is after even more from the Poland international.

"He is giving us great confidence with his performances," the rookie head coach said. "We are more than satisfied with the displays he is putting in on the pitch.

"We know he can still improve because he's a world-class goalkeeper who plays for a great team. We are hoping that he can still do better."